Background: Little is known about the prevalence and correlates of burnout among providers who work in small independent primary care practices (<5 providers).Methods: We conducted a cross-sectional analysis by using data collected from 235 providers practicing in 174 small independent primary care practices in New York City.Results: The rate of provider-reported burnout was 13.5\%. Using bivariate logistic regression, we found higher adaptive reserve scores were associated with lower odds of burnout (odds ratio, 0.12; 95\% CI, 0.02\textendash0.85; P = .034).Conclusion: The burnout rate was relatively low among our sample of providers compared with previous surveys that focused primarily on larger practices. The independence and autonomy providers have in these small practices may provide some protection against symptoms of burnout. In addition, the relationship between adaptive reserve and lower rates of burnout point toward potential interventions for reducing burnout that include strengthening primary care practices\textquoteright learning and development capacity.